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Effect of transferrin glycation induced by high glucose on HK-2 cells in vitro

Effect of transferrin glycation induced by high glucose on HK-2 cells in vitro

July 14, 2025 Category: Blog

Background and objectiveGlycation is a common post-transcriptional modification of proteins.Previous studies have shown that advanced glycation end modified transferrin (AGE-Tf) levels in diabetic rat kidney tissues were increased; however, its role in diabetic nephropathy remains unclear.In this study, differences in glycation degree and Tf sites

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Coproduction in Social Prescribing Initiatives: Protocol for a Scoping Review

July 14, 2025 Category: Blog

BackgroundSocial prescribing (SP) takes a holistic approach to health by linking clients from clinical settings to community programs to address their nonmedical needs.The emerging evidence base for SP demonstrates variability in the design and implementation of different SP initiatives.To effectively address these needs, coproduction among clients

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Lower Serum Irisin Levels Are Associated with Increased Vascular Calcification in Hemodialysis Patients

July 14, 2025 Category: Blog

Molybdenum Grease Background/Aims: Vascular calcification, which involves an active cellular transformation of vascular smooth muscle cells into bone forming cells, is prevalent and predicts mortality in dialysis patients.Its mechanisms are complex and unclear.We presume that irisin, a newly identified myokine also may play roles in vascular calcif

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Review of Therapeutic Options for the Prevention of VTE in Total Joint Arthroplasty

July 14, 2025 Category: Blog

Hip and knee arthroplasty patients are at high risk of perioperative venous thromboembolic events (VTE).VTE has been well studied in this population and it is recommended that total joint arthroplasty recipients receive chemoprophylactic anticoagulation due to risk factors inherent to the surgical intervention.There are few concise resources for th

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